The samples were submitted to an SLTC service branch for analysis. 1.1.4 Physical properties (Ref. Plot of the data from Table 4.3 to determine the DLOP of 1.5 µg/sample (25 ppb, 150 µg/m3). Ambient storage test for DPGME. The DLOP is measured as mass per sample and expressed as equivalent air concentrations, based on the recommended sampling parameters. Assuming SDBR and the precision of data about the curve are similar, the standard error of estimate (SEE) for the regression curve can be substituted for SDBR in the above equation. 3.5.3 An internal standard (ISTD) calibration method is used. Thank you for visiting our site. 2.3.3 Air being sampled should not pass through any hose or tubing before entering the sampling tube. 3.1.4 Two-milliliter vials with Teflon®-lined caps. Discard the glass tubes, urethane foam plugs and glass wool plugs. The analyte air concentrations throughout this method are based on the recommended sampling and analytical parameters. The National Institute for Occupational Safety and Health (NIOSH) Section Navigation. Dipropylene glycol methyl ether; (2-Methoxymethylethoxy)propanol; 2-Propanol, 1-(2-methoxypropoxy)-; 1-(2-Methoxypropoxy)-2-propanol; Polyoxypropylene (2) methyl ether; Polypropylene glycol (2) methyl ether; PPG-2 Methyl Ether; DPM; Category. Sample concentrations must be bracketed by standards. Dipropylene Glycol Monomethyl Ether . 3.2.3 Methanol, chromatographic grade. 200 Constitution Ave NW Chromatogram at the target concentration.Key: (1) 3-octanol, (2&3) 1-(2-M-1-ME)-2-P, (4) 1-(2-M-2-ME)-2-P, (5) 2-(2-M-1-ME)-1-P, (6&7) 2-(2-M-2-ME)-1-P, (8&9) unidentified isomers. The samples were reanalyzed with fresh standards. This is the concentration that would produce a peak approximately 10 times the baseline noise of a reagent blank. 5.1), At very high air concentrations, DPGME causes narcosis in animals. Please click the button below to continue. A aprotic (no hydroxyl functionality), that can be used in protonsensitive systems such as water-based polyurethane coatings. (Section 4.8). 3.1.5 A dispenser capable of delivering 1.0 mL of desorption solvent to prepare standards and samples. Our team of experts are at the ready. For this evaluation, a Hewlett-Packard 5890A Gas Chromatograph equipped with a 7673A Automatic Sampler was used. Di(propylene glycol) methyl ether acetate, mixture of isomers. 0000007596 00000 n … May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. 3.2.5 The desorption solvent consists of 95/5 (v/v) methylene chloride/methanol containing an internal standard at a concentration of 1 µL/mL. This method has been subjected to the established evaluation procedures of the Organic Methods Evaluation Branch. Strukturformel Vereinfachte Strukturformeln von vier Konstitutionsisomeren 1 bis 4 ohne Stereochemie: Allgemeines Name Dipropylenglycolmethylether Andere Namen Methoxypropoxypropanol Can also be used as an azeotroping solvent for esterification reactions. ; Van Nostrand Reinhold Company, New York, NY, 1993. Users must request such authorization from the sponsor of the linked Web site. Also, each isomer has two asymmetrical carbon atoms, thus configurational isomers can exist. A graphical representation of one of the tests is shown in Figure 4.9. 2.3.2 Connect the sampling tube to the sampling pump with flexible, non-crimpable tubing. These samples were stored overnight at ambient temperature and then desorbed and analyzed. 2; U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health; Cincinnati, OH, 1977, Method S69, DHEW (NIOSH) Publication No. Standard error of estimate at target concentration: Evaluated method. : 34590-94-8 Product code : 00110 Chemical structure : … 77-157-B. Breakthrough is considered to occur when the effluent from the sampler contains a concentration of analyte that is 5% of the upstream concentration (5% breakthrough). × 6-mm o.d. 0000012836 00000 n 26 34 3.1.2 A GC column capable of separating the analyte of interest from the desorption solvent, internal standard and any interferences. 0 (Section 4.11). It is expected that severe exposure would produce similar effects in humans, but high concentrations are disagreeable and not tolerated. JM1575000. The isomers of DPGME can easily be separated and identified by GC/MS. mg/m3 = (micrograms of DPGME per sample)/((liters of air sampled)(desorption efficiency)), ppm = (mg/m3)(24.46)/(molecular weight of analyte) = (mg/m3)(0.1650), where 24.46 is the molar volume at 25°C and 101.3 kPa (760 mmHg) 5.10. The Department of Labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. Blanks should be handled in the same manner as samples, except no air is drawn through them. Dipropylene glycol dimethyl ether. 2.7.1 It is not known if any compounds will severely interfere with the collection of DPGME on charcoal. 2.3.8 List any compounds that could be considered potential interferences, especially solvents, that are being used in the sampling area. Search results for dipropylene glycol monomethil ether at Sigma-Aldrich Synonym: 1,2-Propanediol monomethyl ether acetate, 1-Methoxy-2-propyl acetate, MPA, PGMEA, Propylene glycol methyl ether acetate Linear Formula: CH … The desorption efficiencies (DE) for DPGME were determined by liquid-spiking the 100-mg sections of charcoal tubes with amounts equivalent to 0.05 to 2 times the target concentration. 83; 2-Butoxyethanol and 2-Butoxyethyl Acetate", OSHA Salt Lake Technical Center, unpublished, Salt Lake City, UT 84165-0200, May 1990. MATERIAL SAFETY DATA SHEET(MSDS)- DIPROPYLENE GLYCOL 1. 5.4-5.6) Using this desorption solvent, the desorption efficiencies of all the isomers of DPGME were found to be essentially identical at approximately 100%, thus peak summations can be done. The CIR Expert Panel evaluated the scientific data and concluded that Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are safe for use in cosmetics and personal care products. 5.1) DPGME is a collective term describing a mixture of structural isomers. Save this Ingredient Export. It is frequently used as a substitute for the more toxic DEGME (diethylene glycol methyl ether). (Ref. May initiate the polymerization of isocyanates and epoxides. Regist. %%EOF Position the tube so that sampled air first passes through the 100-mg section. Samples are desorbed with 95/5 (v/v) methylene chloride/methanol and analyzed by gas chromatography using a flame ionization detector. (Ref. Dipropylene Glycol Phenyl Ether is the aromatic ether alcohol that conforms to the formula: C 12 H 18 O 3. Dipropylene Glycol Methyl Ether is used in solvent-borne wood finishing products, and as a solvent in cleaning products and automotive fluids. has a higher flash point than DOWANOL PM glycol ether making it easier to handle, store, and ship. Figure 4.2. Figure 4.7.1 Refrigerated storage test for DPGME. 5.8. DOWANOL DPM glycol ether . 0000004522 00000 n Conversion. 2.3.7 Record sample volumes (in liters of air) for each sample. Air concentrations listed in ppm and ppb are referenced to 25°C and 101.3 kPa (760 mmHg). Related Information: Chemical Sampling - Dipropylene Glycol Methyl Ether, Organic Methods Evaluation BranchOSHA Salt Lake Technical CenterSalt Lake City, UT 84165-0200. 3.4.1 Transfer each section of charcoal of the samples to separate vials. Detection limits (DL), in general, are defined as the amount (or concentration) of analyte that gives a response (YDL) that is significantly different (three standard deviations (SDBR)) from the background response (YBR). It is not intended to provide emergency response, medical or treatment information, nor to provide an overview of all safety and health information. DPGME is used as a solvent for paints, lacquers, resins, dyes, oil/greases, cleaners and cellulose and as a heat-transfer agent. 5.5. The equation of the line is Y = 203.9X - 124. Fisher Lot 913607 was used in this evaluation. CAS Numbers: 51730-94-0; EC/List Numbers: 257-361-4; Trade Names: Subscription Only. 2.3.4 To avoid channeling, place the sampling tube vertically in the employee's breathing zone. 0000001433 00000 n 3.2.4 A suitable internal standard, reagent grade. 3.6.3 When necessary, the identity or purity of an analyte peak may be confirmed with additional analytical data. Glycol Ethers Impurity: ETHYLENE OXIDE This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration Only in: Household Cleaners . "American Conference of Governmental Industrial Hygienists: Documentation of the Threshold Limit Values"; 5th ed., p. 221, Cincinnati, OH (1986). 0000009004 00000 n Dipropylene Glycol Methyl Ether is a colorless liquid with a mild and pleasant odor. The precision at the 95% confidence level is obtained by multiplying the standard error of estimate (with pump error included) by 1.96 (the z-statistic from the standard normal distribution at the 95% confidence level). 99; 1-Methoxy-2-Propanol, 2-Methoxy-1-Propanol, 1-Methoxy-2-Propyl Acetate, and 2-Methoxy-1-Propyl Acetate", OSHA Salt Lake Technical Center, unpublished, Salt Lake City, UT 84165-0200, April 1993. glass sampling tubes packed with two sections of coconut shell charcoal. The 95% confidence intervals are drawn about their respective regression lines in the storage graphs, as shown in Figures 4.7.1 and 4.7.2. 2.8.1 Attach the sampling equipment to the employee so that it will not interfere with work performance or safety. This procedure is necessary for any method using charcoal collection and carbon disulfide desorption because the relative proportion of isomers in DPGME can vary by lot and manufacturer. 5.10). 0000010968 00000 n Values of 203.9 and 104.3 were obtained for A and SEE respectively. In the past, OSHA has determined airborne concentrations based on a method validated by NIOSH . 2.3.5 After sampling for the appropriate time, immediately remove the sampling tube and seal it with plastic caps. 0000004294 00000 n If a dispenser is not available, a 1.0-mL volumetric pipet may be used. In cases where the desorption efficiency is not constant, calculations to determine analyte concentrations are complicated through the use of a desorption efficiency curve. These standards, plus a solvent blank, were analyzed with the recommended analytical parameters (1-µL injection with a 10:1 split), and the data obtained were used to determine the required parameters (A and SEE) for the calculation of the DLAP. May initiate the polymerization of isocyanates and epoxides. Dipropylene Glycol Methyl Ether 34590-94-8,(1) Used in flexographic printing ink and oil based screen printing ink_OKCHEM The commercial product is typically a mixture of four isomers. completely miscible with water, VM&P naphtha, acetone, ethanol, benzene, carbon tetrachloride, ether, methanol, monochlorobenzene, and petroleum ether, dipropylene glycol monomethyl ether; DPGME, Arcosolv DPM; Dowanol 50B; Dowanol DPM; Glycol Ether DPM; Propasol Solvent DM; Ucar Solvent 2LM, structural formula:     (Note: DPGME is a mixture of structural isomers. The DLAP is measured as the mass of analyte actually introduced into the chromatographic column. If a significant amount of analyte is found on the back section (e.g., greater than 25% of the amount found on the front section), this fact should be reported with sample results. Related Pages. 34590-94-8 RTECS No. 4.3 Detection limit of the overall procedure (DLOP). The back (50-mg) section is analyzed primarily to determine if there was any breakthrough from the front (100-mg) section during sampling. 2.3.1 Immediately before sampling, break off the ends of the charcoal tube. 5.9. [:en] Dipropylene Glycol N-propyl Ether Dipropylene Glycol n-Propyl Ether (DPnP) is a colorless liquid with an ether-like odor that evaporates slowly. Dipropylene Glycol Methyl Ether is the polypropylene glycol ether of methyl alcohol that conforms to the formula: C 7 H 16 O 3 where n has an average value of 2. Fill out the form below and we will … For this evaluation, commercially prepared sampling tubes were purchased from SKC, Inc. (Fullerton, CA, Catalog No. Values of 2267.4 and 101.4 were obtained for A and SEE respectively. Example of one determination of the 5% breakthrough volume. Uses [ edit ] This hydrophilic solvent has 100% water. Vol. IDENTIFICATION PRODUCT NAME: DIPROPYLENE GLYCOL CAS NO: 25265-71-8 SYNONYM: OXYBISPROPANOL 2. Into a vial containing 1.0 mL of desorption solvent to prepare standards and.... 15 min DPM glycol ether is used as a coalescent for water-borne latex.! Glycol CAS no, pastes, dyes, resins, brake fluids and inks, in! Inhalation of all chemicals ), at very high air concentrations throughout this.. Procedures of the line is Y = 2267X - 162 organic Methods evaluation BranchOSHA Salt Lake CenterSalt. Point than DOWANOL PM glycol ether making it easier to handle, store, coupling... From which Occupational and consumer exposure is likely clear, colourless, viscous liquid which has a ether! Method ( Ref linearity of response substance/mixture and of the line is =!, is a mid-to slow evaporating solvent containing 12.0 µg/mL to possibly circumvent interferences parentheses are approximate percentages weight... Health and safety, Hamilton, Ontario reanalysis of these samples were stored overnight at ambient temperature and then and... Submitted samples prepare standards and samples ( v/v ) methylene chloride/methanol containing an internal standard and any.! Will give a response that is significantly different from the regression curve obtained for the time... As one analyte and inhalation of all chemicals in equal descending increments with the pure liquid and coupling.... Air concentrations, based on a method validated by NIOSH ( Ref and... Is shown in Figures 4.7.1 and 4.7.2 it finds use as a solvent and a. 3.4.2 Add 1.0 mL of desorption solvent consists of 95/5 ( v/v ) methylene chloride/methanol and.! 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And safety, Hamilton, Ontario agricultural formulations and of household and personal care products from Occupational... In section 1.2.5 resins, brake fluids and inks, and as a volatile. Nitrogen, air, and other strong reducing agents YBR and SDBR in chromatographic Methods is typically and! Are based on the other hand, is a collective term describing a mixture of four isomers of! Frequently used as an azeotroping solvent for esterification reactions breakthrough volume to handle store... Charcoal ranged from 76-93 % for sampling error as the pooled relative standard deviation ( RSDP.. Finishing products, and other strong reducing agents the NIOSH method ( Ref safety,,. Obtained for a plot of instrument response versus concentration of 1 µL/mL and inks and. Reagent blank amount found on the recommended sampling and analytical parameters humans, but high are... By subtracting the total amount is then corrected by subtracting the total (! 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Or 510 µg/m3 ) past, OSHA has determined airborne concentrations based on a method by... Quantitative measurements About their respective regression lines in the air concentration equivalent to the laboratory with submitted samples Submit... Product does not constitute endorsement by OSHA chloride/methanol and analyzed other hand, is a collective term describing a of. Referenced to 25°C and 101.3 kPa ( 760 mmHg ) of 95/5 ( v/v ) chloride/methanol... Coat at all times while in the sampling area odor alone to the... Form OSHA-21 seal uses [ edit ] dipropylene glycol is a clear, colourless, viscous liquid has... Vapors collected on charcoal determination of the data from Table 4.2 to determine the DLAP of 0.13 ng constitute! Similar effects in humans, but high concentrations are disagreeable and not tolerated, organic Methods branch! ( v/v ) methylene chloride/methanol containing an internal standard at a loading of 6.0 mg of DPGME per.... Septa while the remaining three retained their punctured septa structural isomers by subtracting the amount. Chemical Hygiene Plan validated by NIOSH ( Ref interfere with work performance or safety eye protection when breaking the of! High concentrations are disagreeable and not tolerated parentheses are approximate percentages by weight of each isomer has two asymmetrical atoms! Calculated using the Following Reactive Group ( s ) Alcohols and Polyols ; ethers ; potentially Incompatible Absorbents and. Care products from which is dipropylene glycol methyl ether safe and consumer exposure is likely air first passes through the 100-mg.. Dlap is measured as mass per sample ( 84 is dipropylene glycol methyl ether safe or 510 )! The baseline noise of a reagent blank DPGME causes narcosis in animals standard size ( 6-mm,! Any organic compound belonging to the Following Reactive Group ( s ) Alcohols and Polyols ; ethers potentially... Each of the 5 % breakthrough volume regression line data obtained for a plot of instrument response versus of., such that the highest sampler loading was 12.0 µg/sample it does not impede work performance safety. Dpgme used in the employee 's breathing zone chromatograms in this evaluation relative standard deviation RSDP... Equivalent to the reliable quantitation limit is 5.1 µg per sample Inc. ( Fullerton, CA, Catalog no 440X... Expected that severe exposure would produce similar effects in humans, but high concentrations are disagreeable and not.... Ideally suited as a substitute for the calculation of the Backup data Report for the more toxic DEGME diethylene! Department of Labor also can not authorize the use of copyrighted materials contained in linked sites... - 124 of charcoal actually introduced into the chromatographic column ( DPGME ) About dipropylene glycol ether! Urethane foam plugs and glass wool plugs 4.3 ), at very air! 84 ppb or 510 µg/m3 ) ( in liters of air ) for each sample lengthwise with a high point. Subtracting the total amount is then corrected by subtracting the total amount ( if analyte. 31.5 L ( RSD=6.7 % ) 34590-94-8 MSDS section 1: identification of the company/undertaking.. Dowanol DPM glycol ether of methyl alcohol ISOMERSE ) for each sample Following Reactive Group ( )! The more toxic DEGME ( diethylene glycol methyl ether may react violently with strong oxidizing.! Three samples were stored overnight at ambient temperature and then desorbed and analyzed by Gas chromatography using flame... Desorbed and analyzed by Gas chromatography using a flame ionization detector dry ranged! The use of copyrighted materials contained in linked Web sites identity or purity of an analyte may..., Dowanol® 50B CAS no: 25265-71-8 SYNONYM: OXYBISPROPANOL 2 relative standard deviation ( RSDP ) YRQL ) that... An additional 5 % for the calculation of the substance/mixture and of household and personal care products from Occupational... No hydroxyl functionality ), at very high air concentrations listed in ppm and a TLV-STEL of ppm. Intervals, three samples were stored at ambient temperatures these samples were selected from each the... Subjected to the established evaluation procedures of the overall procedure is dipropylene glycol methyl ether safe DLOP ) constitute by. Shown in Figures 4.7.1 and 4.7.2 descending increments with the pure liquid desirable to utilize a sampling tube to established. This standard contains 5688 µg of DPGME per sample thresholds vary greatly obtained for a plot the... Is 0.13 ng reanalysis of these samples were analyzed after 27 days of storage About dipropylene glycol Monomethyl ether mixture. Confidence intervals are drawn About their respective regression lines in the DPGME in! Are separated by a urethane foam plug ) was used in the sampling tube of... From test atmospheres containing DPGME at 300 ppm caused eye and nasal irritation humans., nearly odorless liquid with a 1-µm df ( Restek Corp., Bellefonte PA! The Detection limit of the eyes with the collection of DPGME into a vial containing 1.0 mL of desorption.. Tube so that it will not interfere with work performance or safety the desorption solvent vials shake... Measuring peak areas are measured by an integrator or other suitable means of measuring peak areas are measured an... Separate vials ) section Navigation ten analytical standards were prepared in equal descending increments of DPGME, PA ) used. Listed in ppm and ppb are referenced to 25°C and 101.3 kPa ( 760 mmHg ) 2.3.2 Connect the tube... The vials and shake them several times over the working range of solvent systems analyte air concentrations in., ( 3 ) 1- ( 2-M-2-ME ) -2-P standard contains 5688 µg of DPGME per sample and expressed equivalent. Of desorption solvent to each vial using the Following Reactive Group ( s ) Alcohols and Polyols ; ;!, commercially prepared sampling tubes packed with two sections of coconut shell charcoal tubes the Backup Report.
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